Cannot access iTunes updates/account info

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Cannot access iTunes updates/account info
All of a sudden I'm getting "We could not complete itunes store request" messages every time I try to update my apps or try to access my account information.  I've never had this happen before.  Any ideas/solutions would be most helpful!
Repaly
Problem solved, apparently.  Repaired permissions (huge list!), restarted, and all seems to be well.  Also made sure the Keychain Permissions items were also set to "Off" in the process, but not sure which of these steps fixed the issue.
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